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SURGERY

SURGERY PATIENTS AT RISK FOR HERB-ANAESTHESIA INTERACTIONS

The use of herbal medicines and nutraceuticals among patients about to have surgery is becoming more widespread, yet most patients do not tell their physicians. In one study 979 patients who were about to have surgery were asked about their use of herbal remedies and nutraceuticals (supplements not derived from plants). One hundred and seventy (17.4%) patients reported taking such products. The most often used herbs were ginkgo biloba (32.4%), ginseng (26.5%), and garlic (26.5%). Patients are recommended to stop taking herbal preparations at least 2 weeks before elective surgery. Warning about possible side-effects are given for the following herbal remedies:
Ephedra: may interact with antidepressants or antihypertensives to cause increases in blood pressure or heart rate.
Feverfew: may increase bleeding, especially in patients already taking anticoagulants.
Ginkgo: side effects as feverfew.
Garlic: side effects as feverfew.
Ginseng: may decrease effectiveness of some anticoagulants; use associated with hypertension, tachycardia, bleeding.
Kava-kava: may increase effects of some anti-seizure medications or prolong effects of some anaesthetics.
St John’s Wort: may prolong effects of some narcotics and anaesthetics.
Larkin, M
LANCET 2000, 354 (9187) 1362

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